CONTEXT:  Small retrospective study on a biologic treatment for Psoriasis.

IMPACT:  Low


READ TIME:  2 mins


Quality Level Mean [1 – 10]:  7

1. “A real-world study suggests guselkumab is highly effective and safe when used as a treatment for patients with moderate-to-severe plaque psoriasis (PsO) who have received other biologic therapies.” 

2. “The study included electronic medical record data for 50 patients with moderate to severe plaque PsO who had started guselkumab at a hospital in Denmark from 2018 to 2019.” 

3. “At 3 months following initiation of guselkumab, approximately 63.6% of patients experienced a 50% or greater reduction in PASI, and 36.4% of patients experienced a 90% or greater reduction in PASI from baseline.” 

4. “Treatment with guselkumab in this real-world patient population was generally safe.” 

5. “Effectiveness and safety of guselkumab in 50 patients with moderate to severe plaque psoriasis who had previously been treated with other biologics: aguselku retrospective real-world evidence study.” 

Source URL: https://www.dermatologyadvisor.com/home/topics/psoriasis/real-world-study-guselkumab-may-be-effective-for-moderate-to-severe-plaque-psoriasis/