CONTEXT:  Prospective observational study in releasing remitting multiple sclerosis (RRMS) with a relatively old treatment showing a fairly content and stable patient population in Germany | Study conducted between 2015 and 2018 in 190 patients

IMPACT:  Low

READ TIME:  2 mins


Quality Level Mean [1 – 10]:  7

1. “This article was originally published here. BACKGROUND: Peginterferon beta-1a was developed for treatment of relapsing-remitting multiple sclerosis (RRMS) to provide an interferon with increased exposure to facilitate adherence by reducing frequency of application.” 

2. “This non-interventional observational study investigated the adherence to peginterferon beta-1a in real-world clinical practice settings.” 

3. “Adult patients with RRMS (previously treated or treatment-naïve) receiving peginterferon beta-1a (125 µg SC every 2 weeks) were eligible for participation.” 

4. “The primary endpoint was the percentage of patients with overall adherence defined as ⩽10% of injections not administered throughout the 24-month observation period.” 

5. “CONCLUSIONS: Adherence to the bi-weekly treatment with peginterferon beta-1a was very high.” 

Source URL: https://www.docwirenews.com/condition-center/multiple-sclerosis-knowledge-hub/peginterferon-beta-1a-was-associated-with-high-adherence-and-satisfaction-in-patients-with-multiple-sclerosis-in-a-german-real-world-study/