CONTEXT: Some  people lost a small amount of weight whilst in a
study….. Interesting thing here is the reporting of RWE data during a
study lifetime, which has statistical penalties in RCT trials. This is
commonplace in RWE and is one of the benefits of the type of research – you
can look at the data as you go.

READ TIME: 2 mins

*1. “Real-world study shows only 32% of overweight or obese adults with
NAFLD in the U.S. achieved 5% or more weight reduction. DURHAM, N.C., Feb.
2, 2021 /PRNewswire/ — Target RWE, a leading real-world evidence (RWE)
solutions company for the pharmaceutical and biotech industries, shared the
latest data from the ongoing TARGET-NASH observational study, published in
Clinical Gastroenterology Hepatology RWE Health Evidence Solutions logo
(PRNewsfoto/Target RWE)Study shows only 32% of overweight or obese adults
with NAFLD in the U.S. achieved 5% or more weight reduction. The
nonalcoholic steatohepatitis (NASH) study, Weight Loss and Weight Regain in
Usual Clinical Practice: Results from the TARGET-NASH Observational Cohort,
analyzed 2,019 patients enrolled in the TARGET-NASH cohort in the United
States over a median follow-up of 39 months.” *

*2. “Over a median follow-up of 39 months, the study found the following
results:. 32% of patients had weight reduction of 5% or more;. Median time
to initial weight loss was shorter in patients who were obesity class 2/3;
and. Only 25% of patients maintained 5% or more weight loss.” *

*3. “”Our analyses found that among those with initial weight loss, 21%
regained weight back to baseline during follow-up, and 59% of those
patients did so within the first year of weight loss,” said Anna Lok, MD,
Professor of Medicine, University of Michigan, and senior author.” *

*4. “About Target RWE. Target RWE is a health evidence solutions company
generating real-world evidence and regulatory-grade data to advance
clinical, medical, and commercial outcomes.” *

*5. “Target RWE has developed a turnkey health evidence solution which
rapidly aggregates real-world data from a network of sites across the U.S.,
Europe, and other non-U.S. locations.” *

Source URL:
https://finance.yahoo.com/news/target-rwe-shares-weight-loss-181000815.html