Journal of the Association of Physicians in India (JAPI) looks at real-world use of Nimesulide in treating acute febrile illness

CONTEXT:  Research published in the Journal of the Association of Physicians in India (JAPI) looks at real-world use of Nimesulide in treating acute febrile illness.  This retrospective review of 302 electronic medical records (EMR) of patients visiting out-patient clinics at 3 centres in India over a 4 year period.  Nimesulide was found to be well-tolerated and effective in fever management for short term use in real-world clinical practice.


1. “Various clinical trials have established anti-inflammatory and antipyretic properties of Nimesulide in a controlled setting, however, the fever management in real-world settings is quite different.So, researchers aimed to assess the effectiveness of Nimesulide in acute fever management in real-world clinical practice.” 

2. “According to recent reports put forth in Journal Of The Association Of Physicians In India, Nimesulide was found to be well-tolerated and effective as an antipyretic for acute fever management in adults during short-term use in real-world clinical practice.” 

3. “Antipyretics may improve the accompanying responses and reduce the discomfort.Several antipyretic drugs, like Aspirin, Paracetamol, Nimesulide, Ibuprofen, Mefenamic Acid etc., are available and have been used for the management of fever for a long time.” 

4. “For the study design, A retrospective, multicenter study was conducted on electronic medical records (EMR) of 302 patients visiting out-patient departments at three centers between Jan 2016 and Jan 2020 and were prescribed Nimesulide for acute fever.” 

5. “The study outcomes provide the necessary real-world evidence to physicians to consider Nimesulide as an alternative drug of choice to symptomatically manage the acute fever when treating a patient in out-patient department along with other definitive treatments like antibiotics as needed.” 

Source URL:https://www.japi.org/x2946484/effectiveness-of-nimesulide-in-acute-fever-management-in-adults-retrospective-electronic-medical-records-database-study-outcome-in-outpatient-department